Evolutionary science labs by SimBiotic Software

College Labs : Evolution

Evolution is a gradual process, and laboratory experiments showing natural selection or genetic drift with multicellular living organisms are almost impossible in a typical college course. Experiments in macro-evolution are difficult even over the course of a research career! These time constraints have historically limited the use of active-learning techniques in evolution classes. Our evolution labs engage students in "virtual" experimentation on both micro- and macro- evolutionary processes, and put these processes into real-world contexts. They are commonly used as homework to accompany lecture-based evolution classes. Several of our evolution labs were designed with non-majors and introductory biology classes in mind and have been proven effective at conquering common misconceptions.

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Evolution Labs

EvoBeaker: Evolutionary Evidence

A powerful lab for introducing students to the evidence that convinces biologists that life on earth evolved. It covers a key piece of evidence for evolutionary theory, focusing on how related species should have nested sets of traits that reflect their evolutionary tree. ... Read more

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EvoBeaker: Sickle-Cell Alleles

An interactive simulation of the classic malaria and sickle-cell anemia system is used to explore natural selection and genetic drift. Students examine African villages with different malaria death rates. First they use the Hardy-Weinberg equation to calculate the expected proportion of sickle-cell carriers from HbS and HbA allele frequencies. ... Read more

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EvoBeaker: Darwinian Snails

An introductory lab that examines the assumptions behind natural selection using an engaging interactive simulation of green crabs preying on periwinkle snails. Students are able to "violate" each assumption in turn to explore whether evolution by natural selection still occurs. Exercises are targeted to address common misconceptions among biology students. ... Read more

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EvoBeaker: How the Guppy Got Its Spots

Recreate Endler's famous studies of guppy spot brightness in different streams in Trinidad. Students observe the pattern of spot brightness across several pools, then apply classic experimental techniques such as transplants, removals, and behavioral studies to uncover the mechanisms behind the pattern. ... Read more

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EvoBeaker: Flowers and Trees

Introduces students to evolutionary trees using an interactive simulation of Columbine flower diversification. Students observe Columbine populations split and diverge while an expanding evolutionary tree illustrates each population's history. Students further learn to interpret evolutionary trees by creating their own and reconstructing the history of mystery populations. ... Read more

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EvoBeaker: Hardy, Weinberg and Kuru

Uses Kuru disease in New Guinea to teach Hardy-Weinberg equilibrium. Students discover the equilibrium principle from their observations, and play with violating the assumptions to explore the mechanisms of evolution. Also see the effect of heterozygote advantage. Suitable for both intro bio and advanced courses. ... Read more

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EvoBeaker: HIV Clock

When did HIV swing from chimps to humans? Explores the use of RNA sequence changes as a way of measuring time, including discussion of synonymous vs. non-synonymous mutations for detecting selection. At the end, students estimate the age of HIV-1. ... Read more

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EvoBeaker: Domesticating Dogs

Domesticate dogs from two forest wolf populations into several villages. Then trade computers with another student and try to reconstruct their pattern of domestication by sampling dog DNA from each village and using simple evolutionary tree reconstruction algorithms. Along the way, see how mutations accumulate in neutral DNA sequences. ... Read more

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EcoBeaker: Islands and Natural Selection

This laboratory explores how selection can act on two multi-locus traits as the selection regime changes. The example used is beak length and depth of Darwin's finches in wet and dry environments. Students first change the optimal length and/or depth and selection strengths towards those optima and watch what happens to the average beak length and depth in the population. ... Read more

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"The guppies lab was a big hit, and I think the chance to design and test hypotheses is suitable for students at all levels. ...I am very happy with your software."

Dr. Maarten Vonhof
Western Michigan University

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